From the west:

• Take I-90 (Mass Pike) east into Boston
• Stay to the left and take the exit to I-93 north
• Enter the tunnel and take the first exit (# 23 Government Center) to the right
• Stay in the right exit lane then get in left lane to turn left on Cross Street.
• Turn left at Surface Road, then right at New Chardon Street
• Turn right on Canal Street, 66 Canal is in the first block on the left.

Or

• Take Storrow Drive toward Boston
• Storrow becomes Charles Street
• Turn right at Martha Road/Lomasney and continue to Causeway Street
• Turn left onto Causeway. At Canal Street turn right.
• Number 66 is in the second block on the right.

From the South

• Take I-93 north to exit 23, Government Center
• Stay in the right exit lane then get in left lane to turn left on Cross Street.
• Turn left at Surface Road, then right at New Chardon Street
• Turn right on Canal Street, 66 Canal is in the first block on the left.

From the North

• Take I-93 south
• Take Exit 26 to Storrow Drive/North Station
• Continue to Nashua Street, take a sharp right at Nashua St
• Take a left at Lomasney Way
• Turn left onto Causeway Street, then right at Canal Street.

Or

• Take US-1 south toward Boston
• Cross the Mystic River Bridge, pay toll and continue
• Take the I-93 North exit toward Somerville/Charlestown
• Take the exit toward Boston
• Turn slight right onto MA-99 south/New Rutherford Ave.
• Turn right onto Causeway Street
• Turn left onto Canal Street, number 66 is in the second block on the right.

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